Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | CD44 | P16070 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981092 | 0.94 | DRD3 (0.34) | DRD3KMT2AMEN1CXCR3CD44 | |
| Oxalic Acid SCHEMBL6978638 | 0.94 | KDM4E (0.41) | DRD3KMT2AMEN1GAAMAPT | |
| Hydrochloric Acid SCHEMBL6982794 | 0.93 | KMT2A (0.35) | DRD3KMT2AMEN1CXCR3GAA | |
| SCHEMBL3936672 | 0.80 | HTR1A (0.46) | KMT2AMEN1GAADHFRKDM4E | |
| SCHEMBL6983488 | 0.79 | DRD2 (0.41) | DRD3KMT2AMEN1MAPTKDM4E | |
| SCHEMBL6985365 | 0.79 | LMNA (0.42) | — | |
| SCHEMBL8718755 | 0.78 | USP2 (0.35) | DRD3KMT2AMAPTHTR2B | |
| SCHEMBL8713358 | 0.78 | USP2 (0.38) | DRD3KMT2AMAPTHTR2B | |
| Hydrochloric Acid SCHEMBL6979044 | 0.78 | LMNA (0.41) | KMT2AMEN1MAPT | |
| SCHEMBL8713753 | 0.77 | USP2 (0.38) | DRD3KMT2AMEN1MAPTHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |