Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985365 | 0.86 | LMNA (0.42) | SIGMAR1TP53CYP3A4HIF1AMC4R | |
| SCHEMBL4035933 | 0.86 | ALOX15 (0.50) | DRD2SIGMAR1CHRNA7DRD3USP2 | |
| Hydrochloric Acid SCHEMBL6984445 | 0.86 | DRD2 (0.44) | DRD2TP53MAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL6979044 | 0.85 | LMNA (0.41) | SIGMAR1TP53TSHRHIF1AMC4R | |
| Hydrochloric Acid SCHEMBL6986397 | 0.85 | HTR1A (0.41) | DRD2DRD3USP2TP53CYP3A4 | |
| SCHEMBL6976114 | 0.84 | USP2 (0.32) | DRD2DRD3USP2TP53CYP3A4 | |
| SCHEMBL6981065 | 0.84 | SIGMAR1 (0.41) | DRD2SIGMAR1OPRM1SLC6A3MAPT | |
| SCHEMBL6981092 | 0.84 | DRD3 (0.34) | DRD2DRD3USP2TP53CYP3A4 | |
| SCHEMBL9698183 | 0.84 | OPRM1 (0.38) | DRD2SIGMAR1DRD3USP2CYP3A4 | |
| SCHEMBL3936522 | 0.83 | LMNA (0.36) | DRD2DRD3USP2TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112282802-B | Large-span underground cavern explosion-free cutting excavation construction method | 山东文登抽水蓄能有限公司 | 2022-12-09 | — | — | CN | claimed |
| CN-113208199-B | Preparation method of wrinkled bright piece one-piece dress and one-piece dress prepared by same | 雅蒂诗(广州)时装有限公司 | 2022-11-18 | — | — | CN | claimed |
| EP-0483772-B1 | Aminocoumaran derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-09-13 | — | — | EP | claimed |
| US-5376681-A | Aminocoumaran derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-27 | — | — | US | claimed |
| US-11851718-B2 | InDel marker genotype database of Malus and use in identity fingerprinting of germplasm resources | CHINA AGRICULTURAL UNIVERSITY (CN) | 2023-12-26 | — | — | US | disclosed |
| CN-112282802-B | Large-span underground cavern explosion-free cutting excavation construction method | 山东文登抽水蓄能有限公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-113208199-B | Preparation method of wrinkled bright piece one-piece dress and one-piece dress prepared by same | 雅蒂诗(广州)时装有限公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-115104505-A | Decision-making method for field irrigation | 上海兰桂骐技术发展股份有限公司 | 2022-09-27 | — | — | CN | disclosed |
| US-20220090213-A1 | INDEL MARKER GENOTYPE DATABASE OF MALUS AND USE IN IDENTITY FINGERPRINTING OF GERMPLASM RESOURCES | CHINA AGRICULTURAL UNIVERSITY (CN) | 2022-03-24 | — | — | US | disclosed |
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |
| US-5770772-A | 4-FORMYLAMINO-2,3,5-TRIMETHYL-1-(2-METHYL-2-PROPENYLOXY) -BENZENE; ARTERIOSCLEROSIS, BRAIN AND CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-23 | — | — | US | disclosed |
| US-5594154-A | 5-AMINO-2-BROMOMETHYL-2,4,6,7-TETRAMETHYL-2,3-DIHYDROBENZO(B) FURANS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| US-5478844-A | Method of using aminocoumaran derivatives for treating cerebrovascular diseases | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0483772-B1 | Aminocoumaran derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-09-13 | — | — | EP | disclosed |
| US-5376681-A | Aminocoumaran derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-27 | — | — | US | disclosed |
| EP-0483772-A1 | Aminocoumaran derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-05-06 | — | — | EP | disclosed |