Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984135 | 0.86 | TSHR (0.39) | ALDH1A1HIF1AHTTMAPK14TSHR | |
| SCHEMBL6984311 | 0.81 | MAPK14 (0.44) | KDM4EMAPK14DRD1DRD4DRD5 | |
| SCHEMBL6983312 | 0.79 | HTT (0.37) | ALDH1A1HTTTSHRSMN1; SMN2 | |
| SCHEMBL6987843 | 0.77 | HIF1A (0.43) | ALDH1A1HIF1AHTTTSHRSMN1; SMN2 | |
| SCHEMBL6989271 | 0.76 | HIF1A (0.36) | ALDH1A1HIF1AHTTTSHRSMN1; SMN2 | |
| SCHEMBL6984146 | 0.76 | HIF1A (0.42) | ALDH1A1HIF1AHTTTSHRSMN1; SMN2 | |
| SCHEMBL6822507 | 0.74 | HTR7 (0.38) | ALDH1A1KDM4EHTR7SMN1; SMN2HRH3 | |
| SCHEMBL6983980 | 0.74 | HIF1A (0.40) | ALDH1A1KDM4EHIF1AHTTSMN1; SMN2 | |
| SCHEMBL6984423 | 0.74 | ATM (0.38) | ALDH1A1HTT | |
| SCHEMBL6135333 | 0.71 | HTR7 (0.39) | ALDH1A1KDM4EHTR7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313733-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018382-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |