Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987843 | 0.79 | HIF1A (0.43) | HIF1AGAAALDH1A1TSHRMAPK1 | |
| SCHEMBL6984146 | 0.78 | HIF1A (0.42) | HIF1AGAAALDH1A1TSHRMAPK1 | |
| SCHEMBL6984135 | 0.78 | TSHR (0.39) | HIF1AMPOALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6983980 | 0.77 | HIF1A (0.40) | HIF1AGAAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6985009 | 0.76 | ALDH1A1 (0.38) | HIF1AALDH1A1TSHRSMN1; SMN2HRH3 | |
| SCHEMBL6984311 | 0.72 | MAPK14 (0.44) | — | |
| SCHEMBL6984199 | 0.71 | NPC1 (0.42) | HIF1AMPOGAAALDH1A1TSHR | |
| SCHEMBL6981881 | 0.69 | PDE10A (0.43) | GAAALDH1A1TSHRLMNAHTT | |
| SCHEMBL6986812 | 0.68 | ALDH1A1 (0.40) | GAAALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL6984055 | 0.68 | TSHR (0.34) | GAAALDH1A1TSHRMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313733-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018382-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |