Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.46 |
| ▸ | KDM5A | P29375 | 2/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.43 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210605 | 0.85 | CFTR (0.55) | KDM4CKDM5AKDM5BALDH1A1KMT2A | |
| SCHEMBL6236957 | 0.84 | MAPT (0.51) | KDM4CSLC2A1ALDH1A1HPGDKMT2A | |
| SCHEMBL6990355 | 0.81 | SLC2A1 (0.61) | SLC2A1HPGDSLC2A4SLC2A8 | |
| SCHEMBL6987913 | 0.80 | KDM4E (0.48) | PKMALDH1A1NPSR1HPGDKMT2A | |
| SCHEMBL6238400 | 0.79 | SLC2A1 (0.46) | KDM4CKDM5AKDM5BSLC2A1ALDH1A1 | |
| SCHEMBL5210601 | 0.78 | KDM4E (0.56) | KDM4CKDM5AKDM5BALDH1A1KMT2A | |
| SCHEMBL6989757 | 0.77 | MAPT (0.47) | KDM4CKDM5AKDM5BALDH1A1KMT2A | |
| SCHEMBL5214358 | 0.77 | PPARG (0.55) | ALDH1A1NPSR1KMT2AL3MBTL1CFTR | |
| SCHEMBL6991932 | 0.77 | MAPT (0.41) | KDM4CKDM5AKDM5BSLC2A1ALDH1A1 | |
| SCHEMBL6992829 | 0.77 | MAPT (0.46) | SLC2A1ALDH1A1HPGDKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |