Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.45 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 3/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989518 | 0.84 | ALDH1A1 (0.46) | MAPTSMN1; SMN2TP53KDM5AKDM5B | |
| SCHEMBL6987326 | 0.84 | ALDH1A1 (0.43) | MAPTKDM5AKDM5BKDM4AKDM4C | |
| SCHEMBL6235626 | 0.82 | GPBAR1 (0.47) | MAPTKDM5AKDM5BKDM4AKDM4C | |
| SCHEMBL6985789 | 0.82 | HDAC1 (0.51) | MAPTSMN1; SMN2KDM4AKDM4CALDH1A1 | |
| SCHEMBL6988723 | 0.81 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2TP53KDM4AKDM4C | |
| SCHEMBL5210605 | 0.80 | CFTR (0.55) | MAPTKDM5AKDM5BKDM4AKDM4C | |
| SCHEMBL6985142 | 0.77 | PKM (0.46) | MAPTKDM5AKDM5BKDM4CALDH1A1 | |
| SCHEMBL6235628 | 0.75 | KDM4C (0.48) | MAPTKDM5AKDM5BKDM4AKDM4C | |
| SCHEMBL6985787 | 0.74 | KDM4A (0.50) | MAPTKDM5AKDM5BKDM4AKDM4C | |
| SCHEMBL6238400 | 0.74 | SLC2A1 (0.46) | MAPTKDM5AKDM5BKDM4AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |