Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | YAP1 | P46937 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | LOX | P28300 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985248 | 0.84 | MAPT (0.42) | PTGER4MAPK1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6985141 | 0.83 | AVPR2 (0.47) | AVPR2MAPK1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7410532 | 0.81 | CHRM2 (0.41) | PTGER4MAPK1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6981829 | 0.80 | POLB (0.39) | AVPR2PTGER4NPC1 | |
| SCHEMBL6985353 | 0.79 | ALDH1A1 (0.46) | AVPR2PTGER4MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL6987049 | 0.78 | FKBP1A (0.42) | PTGER4CNR1MAPK1SMN1; SMN2 | |
| SCHEMBL6986544 | 0.77 | PTGER4 (0.39) | AVPR2PTGER4MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL6979177 | 0.77 | CCR5 (0.39) | PTGER4MAPK1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6977399 | 0.77 | PTGER4 (0.42) | PTGER4MAPK1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6986437 | 0.76 | PTGER4 (0.41) | AVPR2PTGER4MAPK1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |