Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410532 | 0.90 | CHRM2 (0.41) | ALDH1A1PTGER4SMN1; SMN2HPGDDPP8 | |
| SCHEMBL6981829 | 0.87 | POLB (0.39) | ALDH1A1PTGER4HPGDTSHRNPC1 | |
| SCHEMBL6987049 | 0.85 | FKBP1A (0.42) | ALDH1A1PTGER4SMN1; SMN2HPGDTSHR | |
| SCHEMBL6985248 | 0.82 | MAPT (0.42) | ALDH1A1PTGER4SMN1; SMN2HPGDMAPT | |
| SCHEMBL6985351 | 0.81 | ALDH1A1 (0.54) | ALDH1A1 | |
| SCHEMBL6986544 | 0.80 | PTGER4 (0.39) | ALDH1A1PTGER4SMN1; SMN2HPGDMAPT | |
| SCHEMBL6977399 | 0.80 | PTGER4 (0.42) | ALDH1A1PTGER4SMN1; SMN2HPGDMAPT | |
| SCHEMBL6985146 | 0.79 | AVPR2 (0.40) | PTGER4SMN1; SMN2MAPTNPC1MAPK1 | |
| SCHEMBL6979177 | 0.78 | CCR5 (0.39) | ALDH1A1PTGER4SMN1; SMN2HPGDMAPT | |
| SCHEMBL6979727 | 0.78 | TSHR (0.40) | ALDH1A1PTGER4SMN1; SMN2HPGDDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |