Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983249 | 0.92 | KMT2A (0.44) | KMT2AMEN1POLBALDH1A1MAPK1 | |
| SCHEMBL6991687 | 0.90 | KMT2A (0.42) | KMT2AMEN1POLBALDH1A1MAPK1 | |
| SCHEMBL6981005 | 0.88 | POLB (0.42) | KMT2AMEN1POLBALDH1A1MAPK1 | |
| SCHEMBL6988211 | 0.86 | POLB (0.40) | KMT2AMEN1POLBALDH1A1MAPK1 | |
| SCHEMBL6989571 | 0.83 | KMT2A (0.50) | KMT2AMEN1POLBALDH1A1MAPK1 | |
| SCHEMBL6985145 | 0.79 | KMT2A (0.56) | KMT2AMEN1POLBALDH1A1MAPK1 | |
| SCHEMBL6989465 | 0.77 | NPC1 (0.41) | KMT2AMEN1POLBHTTRAB9A | |
| SCHEMBL6990394 | 0.77 | NPC1 (0.40) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL6989095 | 0.76 | KMT2A (0.50) | KMT2AMEN1POLBALDH1A1MAPK1 | |
| SCHEMBL6986333 | 0.75 | MEN1 (0.48) | KMT2AMEN1POLBALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358160-A1 | AMINAL DIONES AS POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2003-11-05 | — | — | EP | claimed |
| WO-2002062761-A1 | AMINAL DIONES AS POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2002-08-15 | — | — | WO | claimed |
| EP-1358160-A1 | AMINAL DIONES AS POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002062761-A1 | AMINAL DIONES AS POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2002-08-15 | — | — | WO | disclosed |