Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.37 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988211 | 0.93 | POLB (0.40) | KMT2ACYP1A2CYP3A4POLBRAB9A | |
| SCHEMBL6983249 | 0.91 | KMT2A (0.44) | KMT2APOLBRAB9ANPC1ALDH1A1 | |
| SCHEMBL6985151 | 0.90 | KMT2A (0.55) | KMT2APOLBRAB9ANPC1ALDH1A1 | |
| SCHEMBL6981005 | 0.87 | POLB (0.42) | KMT2ACYP1A2CYP3A4POLBRAB9A | |
| SCHEMBL6989465 | 0.80 | NPC1 (0.41) | KMT2ACYP1A2POLBRAB9ANPC1 | |
| SCHEMBL6991619 | 0.80 | TYK2 (0.37) | — | |
| SCHEMBL6986478 | 0.79 | KMT2A (0.43) | KMT2AUSP2CYP1A2CYP3A4POLB | |
| SCHEMBL6990809 | 0.76 | MEN1 (0.48) | KMT2ACYP1A2CYP3A4POLBRAB9A | |
| SCHEMBL6990394 | 0.76 | NPC1 (0.40) | KMT2ARAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL6986333 | 0.74 | MEN1 (0.48) | KMT2APOLBRAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358160-A1 | AMINAL DIONES AS POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2003-11-05 | — | — | EP | claimed |
| WO-2002062761-A1 | AMINAL DIONES AS POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2002-08-15 | — | — | WO | claimed |