Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PPOX | P50336 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983685 | 0.79 | ACHE (0.47) | TSHRALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL6702783 | 0.73 | HTR4 (0.47) | TSHRALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL6703970 | 0.71 | ACHE (0.43) | TSHRALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL6985171 | 0.68 | TSHR (0.46) | TSHRALDH1A1LMNAKMT2AKDM4E | |
| SCHEMBL6987576 | 0.67 | TSHR (0.43) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL11480696 | 0.66 | PTGDR2 (0.46) | MEN1KMT2A | |
| SCHEMBL6699852 | 0.66 | ACHE (0.47) | TSHRALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL14309294 | 0.65 | TAAR1 (0.63) | TSHRALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL8132262 | 0.65 | TAAR1 (0.51) | TSHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6987698 | 0.65 | NPSR1 (0.45) | ALDH1A1NPC1RAB9ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |