Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 5/20 | 0.38 |
| ▸ | CCR3 | P51677 | 4/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.36 |
| ▸ | RXFP2 | Q8WXD0 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988752 | 0.88 | ALDH1A1 (0.43) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL6986644 | 0.82 | F10 (0.43) | ALDH1A1F10CHRM2 | |
| SCHEMBL6990232 | 0.80 | PYGL (0.42) | SMYD3 | |
| SCHEMBL6987482 | 0.80 | SMYD3 (0.37) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL6986945 | 0.78 | F10 (0.53) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL6985167 | 0.78 | F10 (0.53) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL6987891 | 0.75 | F10 (0.38) | KDM4EALDH1A1F10CCR3 | |
| SCHEMBL6982644 | 0.75 | F10 (0.38) | F10CCR3CHRM2 | |
| SCHEMBL5868197 | 0.74 | KDM4E (0.46) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL5868023 | 0.73 | KDM4E (0.48) | KDM4EALDH1A1MAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289954-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096303-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |