Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985512 | 0.80 | KDM4E (0.45) | SMYD3F10KDM4EALDH1A1MAPT | |
| SCHEMBL6989019 | 0.75 | FAAH (0.42) | F10HRH3HTR4ACHEALDH1A1 | |
| SCHEMBL5868417 | 0.74 | SMYD3 (0.38) | SMYD3F10MAPK14HRH3HTR4 | |
| Hydrochloric Acid SCHEMBL5868316 | 0.73 | F10 (0.36) | SMYD3F10MAPK11MAPK14HRH3 | |
| SCHEMBL6987333 | 0.73 | PYGL (0.42) | SMYD3HRH3HTR4VCP | |
| SCHEMBL6986945 | 0.72 | F10 (0.53) | SMYD3F10MAPK14KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6985167 | 0.72 | F10 (0.53) | SMYD3F10MAPK14HRH3KDM4E | |
| SCHEMBL6988752 | 0.70 | ALDH1A1 (0.43) | SMYD3F10HTR4SIGMAR1KDM4E | |
| Trifluoroacetic Acid SCHEMBL5868462 | 0.70 | F10 (0.36) | SMYD3F10MAPK11MAPK14HRH3 | |
| SCHEMBL5868347 | 0.70 | SMYD3 (0.35) | SMYD3F10HRH3HTR4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289954-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096303-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |