Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 17/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987333 | 0.88 | PYGL (0.42) | PYGLHRH4SMYD3NHERF1 | |
| SCHEMBL6984406 | 0.87 | CHRM1 (0.44) | PYGLHRH4SMYD3NHERF1 | |
| SCHEMBL6985512 | 0.80 | KDM4E (0.45) | SMYD3 | |
| SCHEMBL6986644 | 0.77 | F10 (0.43) | — | |
| SCHEMBL5868431 | 0.75 | PYGL (0.47) | PYGLHRH4SMYD3 | |
| SCHEMBL5868019 | 0.74 | PYGL (0.43) | PYGLHRH4SMYD3 | |
| SCHEMBL5868163 | 0.72 | PYGL (0.47) | PYGLHRH4 | |
| Hydrochloric Acid SCHEMBL5868302 | 0.71 | PYGL (0.41) | PYGLHRH4 | |
| SCHEMBL6988752 | 0.69 | ALDH1A1 (0.43) | SMYD3 | |
| SCHEMBL7254522 | 0.69 | HRH4 (0.47) | PYGLHRH4SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289954-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096303-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |