Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 5/20 | 0.37 |
| ▸ | PPOX | P50336 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989202 | 0.72 | TSHR (0.39) | TSHRACHEPPOXLMNATP53 | |
| SCHEMBL6699193 | 0.72 | ACHE (0.46) | TSHRACHELMNAHTR4KDM4E | |
| SCHEMBL6699852 | 0.68 | ACHE (0.47) | TSHRACHELMNAHTR4KDM4E | |
| SCHEMBL6985171 | 0.67 | TSHR (0.46) | TSHRPPOXLMNATP53PKM | |
| SCHEMBL6983688 | 0.67 | TSHR (0.46) | TSHRPPOXLMNATP53PKM | |
| SCHEMBL6987576 | 0.64 | TSHR (0.43) | TSHRACHELMNAHTR4KDM4E | |
| SCHEMBL2481341 | 0.63 | HTR4 (0.66) | TSHRACHEHTR4SIGMAR1ALDH1A1 | |
| SCHEMBL2480715 | 0.62 | TSHR (0.44) | TSHRACHELMNAHTR4KDM4E | |
| SCHEMBL2480716 | 0.62 | TSHR (0.44) | TSHRACHELMNAHTR4KDM4E | |
| SCHEMBL8140543 | 0.62 | KDM4E (0.43) | TSHRACHELMNATP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |