Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987042 | 0.88 | PDE10A (0.37) | ALDH1A1KMT2AMTORSMN1; SMN2PDE10A | |
| SCHEMBL6983287 | 0.84 | PDE1A (0.36) | ALDH1A1KMT2AMTORSMN1; SMN2PDE10A | |
| SCHEMBL6987206 | 0.84 | PDE1A (0.36) | ALDH1A1KMT2AMTORSMN1; SMN2PDE10A | |
| SCHEMBL6982802 | 0.84 | PDE1A (0.36) | ALDH1A1KMT2AMTORSMN1; SMN2PDE10A | |
| SCHEMBL6989453 | 0.80 | KMT2A (0.42) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL14500140 | 0.76 | DPP4 (0.49) | KMT2AHRH3SMN1; SMN2 | |
| SCHEMBL6990765 | 0.75 | PTGS2 (0.44) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6983913 | 0.75 | HRH3 (0.47) | HRH3SMN1; SMN2 | |
| SCHEMBL6986812 | 0.74 | ALDH1A1 (0.40) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6990503 | 0.70 | TSHR (0.39) | ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313733-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018382-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |