Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FPR1 | P21462 | 2/20 | 0.39 |
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983538 | 0.91 | FFAR1 (0.41) | RXRARXRBRXRGHDAC6FFAR1 | |
| SCHEMBL6983660 | 0.88 | PTGER4 (0.40) | FPR1FPR2NPC1TSHRMEN1 | |
| SCHEMBL7407513 | 0.88 | RAB9A (0.44) | FFAR1FPR1FPR2TSHRMEN1 | |
| SCHEMBL6986817 | 0.87 | THRB (0.42) | HDAC6ATMFPR1FPR2TSHR | |
| SCHEMBL6986437 | 0.86 | PTGER4 (0.41) | HDAC6ATMFFAR1FPR1FPR2 | |
| SCHEMBL6985566 | 0.86 | PARP14 (0.40) | ATMFPR1FPR2NPC1TDP1 | |
| SCHEMBL6985381 | 0.86 | MMP1 (0.45) | HDAC6ATMFPR1FPR2KMT2A | |
| SCHEMBL6985322 | 0.84 | GAA (0.41) | FPR1FPR2NPC1TSHRMEN1 | |
| SCHEMBL6985295 | 0.84 | MAPT (0.45) | FPR1FPR2MEN1ALDH1A1KMT2A | |
| SCHEMBL6976287 | 0.83 | NOTUM (0.38) | HDAC6ATMFPR1FPR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |