Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 2/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.49 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | KDM6B | O15054 | 1/20 | 0.49 |
| ▸ | TET3 | O43151 | 1/20 | 0.49 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KDM5C | P41229 | 1/20 | 0.49 |
| ▸ | ASPH | Q12797 | 1/20 | 0.49 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.49 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.49 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.49 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.49 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.49 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.49 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.49 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986939 | 0.92 | KMT2A (0.48) | KDM5AKDM4CKDM5BKDM4EALDH1A1 | |
| SCHEMBL6988711 | 0.77 | CA12 (0.51) | KDM5AKDM4CKDM5BKDM4EKDM6B | |
| SCHEMBL5808530 | 0.75 | ALDH1A1 (0.65) | KDM5AKDM4CKDM5BKDM4EKDM6B | |
| SCHEMBL6989313 | 0.73 | SMN1; SMN2 (0.47) | KDM5AKDM4CKDM5BKDM4EKDM6B | |
| SCHEMBL17819893 | 0.73 | FTO (0.67) | KDM5AKDM4CKDM5BKDM4EKDM6B | |
| SCHEMBL3854386 | 0.72 | KDM5B (0.57) | KDM5AKDM4CKDM5BKDM4EKDM6B | |
| SCHEMBL1920448 | 0.72 | FTO (0.61) | KDM5AKDM4CKDM5BKDM4EKDM6B | |
| SCHEMBL177390 | 0.70 | PLA2G4B (0.82) | ALDH1A1SMN1; SMN2PKMTP53NFKB1 | |
| SCHEMBL1992514 | 0.70 | MAPT (0.57) | KDM5AKDM4CKDM5BKDM4EKDM6B | |
| SCHEMBL27639521 | 0.70 | KDM4E (0.52) | KDM5AKDM4CKDM5BKDM4EKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |