Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 6/20 | 0.61 |
| ▸ | KDM5C | P41229 | 3/20 | 0.61 |
| ▸ | ALKBH5 | Q6P6C2 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | KDM6B | O15054 | 2/20 | 0.61 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.61 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.61 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.61 |
| ▸ | KDM4A | O75164 | 2/20 | 0.61 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.61 |
| ▸ | TET3 | O43151 | 1/20 | 0.61 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | KDM5A | P29375 | 1/20 | 0.61 |
| ▸ | ASPH | Q12797 | 1/20 | 0.61 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.61 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.61 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.61 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29466587 | 0.90 | JMJD6 (0.57) | KDM5CKDM4CKDM5BKDM5ACYP1A2 | |
| SCHEMBL930636 | 0.90 | JMJD6 (0.57) | KDM5CKDM4CKDM5BKDM5ACYP1A2 | |
| SCHEMBL16578099 | 0.87 | KDM4E (0.61) | FTOKDM5CALKBH5KDM4EKDM6B | |
| SCHEMBL9297593 | 0.87 | CYP1A2 (0.49) | FTOKDM5CALKBH5KDM4EKDM6B | |
| SCHEMBL8950955 | 0.86 | MMP2 (0.48) | FTOKDM5CALKBH5KDM4EKDM6B | |
| SCHEMBL24604371 | 0.84 | CYP1A2 (0.46) | FTOKDM5CALKBH5KDM4EKDM6B | |
| SCHEMBL28033804 | 0.83 | MAPT (0.60) | ALDH1A1MAPTCYP1A2JMJD6GABRP | |
| SCHEMBL28990167 | 0.83 | CYP2C9 (0.54) | FTOKDM5CALKBH5KDM4EKDM6B | |
| SCHEMBL28271627 | 0.83 | KDM5C (0.69) | KDM5CKDM4EKDM6BKDM4CKDM2A | |
| Bromide SCHEMBL9298199 | 0.82 | JMJD6 (0.44) | FTOKDM5CALKBH5KDM4EKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807886-B2 | Process for the preparation of copolymers derived from 2,4- or 2,5-pyridinedicarboxylic acid | BIOME BIOPLASTICS LIMITED (GB) | 2023-11-07 | — | — | US | disclosed |
| EP-3307901-B1 | PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID | BIOME BIOPLASTICS LTD (GB) | 2022-04-27 | — | — | EP | disclosed |
| US-11045407-B2 | Process for treating keratin fibres with a pyridinedicarboxylic acid compound | L'OREAL (FR) | 2021-06-29 | — | — | US | disclosed |
| US-10857087-B2 | Process for treating keratin fibres with a polysaccharide and a pyridinedi-carboxylic acid compound | L'OREAL (FR) | 2020-12-08 | — | — | US | disclosed |
| CN-104877001-B | Antifungal formulations | 西尼克斯公司 | 2020-07-03 | — | — | CN | disclosed |
| US-20180148752-A1 | PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM | BIOME BIOPLASTICS LIMITED (GB) | 2018-05-31 | — | — | US | disclosed |
| WO-2016202875-A1 | PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM | BIOME BIOPLASTICS LIMITED (GB) | 2016-12-22 | — | — | WO | disclosed |
| WO-2016142635-A1 | METHOD FOR THE COSMETIC TREATMENT OF THICK HAIR WITH A PYRIDINE DICARBOXYLIC ACID COMPOUND | L'OREAL (FR) | 2016-09-15 | — | — | WO | disclosed |
| US-20160228346-A1 | PROCESS FOR TREATING KERATIN FIBRES WITH A POLYSACCHARIDE AND A PYRIDINEDI-CARBOXYLIC ACID COMPOUND | L'OREAL (FR) | 2016-08-11 | — | — | US | disclosed |
| US-20160228346-A1 | PROCESS FOR TREATING KERATIN FIBRES WITH A POLYSACCHARIDE AND A PYRIDINEDI-CARBOXYLIC ACID COMPOUND | L'OREAL (FR) | 2016-08-11 | — | — | US | disclosed |
| CN-103204852-A | Heteroaryl amide analogues as P2X7 antagonists | LUNDBECK & CO AS H | 2013-07-17 | — | — | CN | disclosed |
| US-8188085-B2 | Antifungal agents | MERCK SHARP & DOHME CORP. (US) | 2012-05-29 | — | — | US | disclosed |
| US-8188085-B2 | Antifungal agents | MERCK SHARP & DOHME CORP. (US) | 2012-05-29 | — | — | US | disclosed |
| CN-102176827-A | Antifungal formulations | MERCK SHARP & DOHME | 2011-09-07 | — | — | CN | disclosed |
| EP-2326181-A1 | ANTIFUNGAL AGENTS | Merck Sharp & Dohme Corp. (US) | 2011-06-01 | — | — | EP | disclosed |
| CN-101772498-A | As P2X7Heteroaryl amide analogs of antagonists | LUNDBECK & CO AS H | 2010-07-07 | — | — | CN | disclosed |
| US-20100113439-A1 | Antifungal agents | MERCK & CO., INC. (US) | 2010-05-06 | — | — | US | disclosed |
| US-20100113439-A1 | Antifungal agents | MERCK & CO., INC. (US) | 2010-05-06 | — | — | US | disclosed |
| WO-2010019204-A1 | ANTIFUNGAL AGENTS | MERCK SHARP & DOHME CORP. (US) | 2010-02-18 | — | — | WO | disclosed |
| WO-2010019204-A1 | ANTIFUNGAL AGENTS | MERCK SHARP & DOHME CORP. (US) | 2010-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11045407-B2 | Process for treating keratin fibres with a pyridinedicarboxylic acid compound | KRT18, CUTA, HKDC1 | FTO 1830/4885KDM5C 15/4885ALKBH5 1172/4885 |
| US-11807886-B2 | Process for the preparation of copolymers derived from 2,4- or 2,5-pyridinedicarboxylic acid | HPD, PGD, PCCA | FTO 78/4885KDM5C 261/4885ALKBH5 205/4885 |
| US-20160228346-A1 | PROCESS FOR TREATING KERATIN FIBRES WITH A POLYSACCHARIDE AND A PYRIDINEDI-CARBOXYLIC ACID COMPOUND | KRT18, HKDC1, PHYKPL | FTO 889/4885KDM5C 6/4885ALKBH5 1303/4885 |
| US-20100113439-A1 | Antifungal agents | GMDS, GBA3, UGGT1 | FTO 2493/4885KDM5C 3417/4885ALKBH5 3149/4885 |
| US-20180148752-A1 | PROCESS FOR THE PREPARATION OF 2,4- OR 2,5-PYRIDINEDICARBOXYLIC ACID AND COPOLYMERS DERIVED THEREFROM | HPD, PCCA, MVD | FTO 34/4885KDM5C 536/4885ALKBH5 104/4885 |
| US-10857087-B2 | Process for treating keratin fibres with a polysaccharide and a pyridinedi-carboxylic acid compound | KRT18, HKDC1, PHYKPL | FTO 889/4885KDM5C 6/4885ALKBH5 1303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.