Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | ALPI | P09923 | 1/20 | 0.30 |
| ▸ | ALPG | P10696 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23676453 | 0.84 | GPR84 (0.47) | — | |
| SCHEMBL6979886 | 0.83 | KDM4E (0.41) | ALPLALPIALPG | |
| SCHEMBL22166615 | 0.81 | ALPL (0.32) | ALPLALPIALPG | |
| SCHEMBL6985646 | 0.75 | SCN10A (0.37) | SCN10AALPLALPIALPGAAK1 | |
| SCHEMBL6986516 | 0.74 | SCN10A (0.45) | SCN10AALPLALPIALPGAAK1 | |
| SCHEMBL13544178 | 0.73 | GAA (0.42) | — | |
| SCHEMBL10061820 | 0.71 | PARP1 (0.39) | — | |
| SCHEMBL23676463 | 0.69 | GPR84 (0.43) | — | |
| SCHEMBL22962268 | 0.69 | KDM4E (0.40) | ALPLALPIALPG | |
| SCHEMBL22962129 | 0.68 | KDM4E (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324029-A1 | THERAPEUTIC AGENTS | MERCK SHARP & DOHME CORP. | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324029-A1 | THERAPEUTIC AGENTS | PSEN2, PSEN1, BACE2 | SCN10A 3312/4885ALPL 3794/4885ALPI 1639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.