Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.49 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987138 | 0.86 | KDM1A (0.51) | — | |
| SCHEMBL31188605 | 0.80 | TAAR1 (0.55) | TP53ALDH1A1 | |
| SCHEMBL11626087 | 0.77 | VNN1 (0.63) | POLBTP53ALDH1A1 | |
| SCHEMBL11626058 | 0.77 | VNN1 (0.67) | ALDH1A1DDR1 | |
| SCHEMBL23447721 | 0.76 | MLYCD (0.77) | POLBTP53ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11627866 | 0.76 | VNN1 (0.65) | ALDH1A1DDR1 | |
| SCHEMBL6981160 | 0.75 | PTGES (0.49) | — | |
| SCHEMBL23447718 | 0.75 | LMNA (0.74) | POLBTP53ALDH1A1 | |
| SCHEMBL21858046 | 0.74 | CYP3A4 (0.67) | — | |
| SCHEMBL30739602 | 0.73 | POLB (0.78) | POLBTP53ALDH1A1DDR1TP53BP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1324999-A1 | NOVEL AMINOPHENYL PIPERAZINE OR AMINOPHENYL PIPERIDINE DERIVATIVES INHIBITING PRENYL TRANSFERASE PROTEINS AND METHODS FOR PREPARING SAME | PIERRE FABRE MEDICAMENT (FR) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002030927-A1 | NOVEL AMINOPHENYL PIPERAZINE OR AMINOPHENYL PIPERIDINE DERIVATIVES INHIBITING PRENYL TRANSFERASE PROTEINS AND METHODS FOR PREPARING SAME | PIERRE FABRE MEDICAMENT (FR) | 2002-04-18 | — | — | WO | disclosed |