Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | LSS | P48449 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987133 | 0.86 | POLB (0.55) | — | |
| SCHEMBL31188605 | 0.82 | TAAR1 (0.55) | HRH3 | |
| SCHEMBL6981160 | 0.77 | PTGES (0.49) | — | |
| SCHEMBL5959133 | 0.77 | HIF1A (0.54) | — | |
| SCHEMBL21857890 | 0.75 | CYP3A4 (0.70) | — | |
| SCHEMBL11628816 | 0.75 | NAMPT (0.67) | KDM1AHDAC1LSS | |
| Hydrochloric Acid SCHEMBL11627973 | 0.74 | SORT1 (0.65) | KDM1AHDAC1LSS | |
| SCHEMBL13724678 | 0.73 | CES2 (0.57) | LSS | |
| SCHEMBL14082728 | 0.73 | KMT2A (0.53) | KDM1AHDAC1 | |
| SCHEMBL11625535 | 0.72 | ALDH1A1 (0.76) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1324999-A1 | NOVEL AMINOPHENYL PIPERAZINE OR AMINOPHENYL PIPERIDINE DERIVATIVES INHIBITING PRENYL TRANSFERASE PROTEINS AND METHODS FOR PREPARING SAME | PIERRE FABRE MEDICAMENT (FR) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002030927-A1 | NOVEL AMINOPHENYL PIPERAZINE OR AMINOPHENYL PIPERIDINE DERIVATIVES INHIBITING PRENYL TRANSFERASE PROTEINS AND METHODS FOR PREPARING SAME | PIERRE FABRE MEDICAMENT (FR) | 2002-04-18 | — | — | WO | disclosed |