Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986812 | 0.84 | ALDH1A1 (0.40) | ALDH1A1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL6979346 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL6982469 | 0.80 | CYP2C9 (0.39) | ALDH1A1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL6985846 | 0.78 | BCL2 (0.41) | ALDH1A1KMT2AHTTSMN1; SMN2GAA | |
| SCHEMBL6987183 | 0.77 | TSHR (0.45) | ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL6987419 | 0.75 | ALDH1A1 (0.43) | ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL6983706 | 0.74 | HTT (0.36) | ALDH1A1KMT2AHTTSMN1; SMN2GAA | |
| SCHEMBL6986605 | 0.73 | HTT (0.48) | ALDH1A1KMT2AHTTSMN1; SMN2GAA | |
| SCHEMBL6822342 | 0.73 | LMNA (0.41) | ALDH1A1POLBNPY5RLMNAHTT | |
| SCHEMBL6990503 | 0.73 | TSHR (0.39) | ALDH1A1KMT2ALMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313733-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018382-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |