SCHEMBL698777

SCHEMBL698777

COc1c(O)cc2c(c1O)C(=O)C(O)C(c1ccc(O)c(O)c1)O2

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 3/20 0.73
SYNJ2 O15056 3/20 0.72
RECQL P46063 2/20 0.62
SOST Q9BQB4 2/20 0.62
MEN1 O00255 1/20 0.62
KMT2A Q03164 1/20 0.62
KDM4E B2RXH2 1/20 0.62
POLB P06746 1/20 0.62
GAA P10253 1/20 0.62
MAPT P10636 1/20 0.62
CYP1A2 P05177 1/20 0.62
CYP3A4 P08684 1/20 0.62
ALOX15 P16050 1/20 0.62
ALOX12 P18054 1/20 0.62
NFKB1 P19838 1/20 0.62
MAPK1 P28482 1/20 0.62
HIF1A Q16665 1/20 0.62
HSD17B10 Q99714 1/20 0.62
IDO1 P14902 1/20 0.60
NSD2 O96028 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20450287 1.00 XDH (0.73) XDHSYNJ2RECQLSOSTMEN1
Alnustinol SCHEMBL17503285 0.88 NPC1 (0.62) XDHSYNJ2RECQLSOSTMEN1
SCHEMBL31612512 0.85 SYNJ2 (0.79) XDHSYNJ2RECQLSOSTMEN1
SCHEMBL17157085 0.84 SYNJ2 (1.00) XDHSYNJ2RECQLSOSTMEN1
SCHEMBL18517028 0.84 SYNJ2 (1.00) XDHSYNJ2RECQLSOSTMEN1
SCHEMBL24433093 0.84 SYNJ2 (1.00) XDHSYNJ2RECQLSOSTMEN1
SCHEMBL15773442 0.84 SYNJ2 (1.00) XDHSYNJ2RECQLSOSTMEN1
SCHEMBL20450284 0.83 ABCB1 (0.53) XDHSYNJ2RECQLSOSTMEN1
SCHEMBL30873076 0.83 ABCB1 (0.53) XDHSYNJ2RECQLSOSTMEN1
SCHEMBL30834907 0.83 XDH (0.53) XDHSYNJ2RECQLSOSTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2026-04-30 US disclosed
EP-4593631-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME Mars, Incorporated (US) 2025-08-06 EP disclosed
CN-119968127-A Animal food compositions with improved palatability and customizable properties and methods of making the same 玛氏公司 2025-05-09 CN disclosed
WO-2024073025-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2024-04-04 WO disclosed
EP-4344552-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2024-04-03 EP disclosed
EP-3356356-B1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED (US) 2021-05-26 EP disclosed
US-10392371-B2 Compounds useful as modulators of TRPM8 SENOMYX, INC. (US) 2019-08-27 US disclosed
US-20190177308-A9 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 SENOMYX, INC. 2019-06-13 US disclosed
US-20180273517-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 SENOMYX INC (US) 2018-09-27 US disclosed
EP-3356356-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 Senomyx, Inc. (US) 2018-08-08 EP disclosed
US-7919236-B2 G-proteins GIVAUDAN SA (CH) 2011-04-05 US disclosed
US-20090176266-A1 FUNCTIONAL METHOD TO IDENTIFY TASTANTS GIVAUDAN S.A. (CH) 2009-07-09 US disclosed
EP-2007805-A1 NUCLEIC ACID, POLYPEPTIDE AND ITS USE Givaudan SA (CH) 2008-12-31 EP disclosed
EP-2008095-A1 FUNCTIONAL METHOD TO IDENTIFY TASTANTS Givaudan SA (CH) 2008-12-31 EP disclosed
EP-1581555-B1 CHIMERIC ALPHA Q-GUSTDUCIN G-PROTEINS GIVAUDAN SA (CH) 2008-04-30 EP disclosed
WO-2007121600-A1 NUCLEIC ACID, POLYPEPTIDE AND ITS USE GIVAUDAN SA (CH) 2007-11-01 WO disclosed
WO-2007121599-A1 FUNCTIONAL METHOD TO IDENTIFY TASTANTS GIVAUDAN SA (CH) 2007-11-01 WO disclosed
US-20060275765-A1 G-proteins GIVAUDAN SA (CH) 2006-12-07 US disclosed
EP-1581555-A2 G-PROTEINS Givaudan SA (CH) 2005-10-05 EP disclosed
WO-2004055048-A2 CHIMERIC ALPHA Q-GUSTDUCIN G-PROTEINS GIVAUDAN SA (CH) 2004-07-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10392371-B2 Compounds useful as modulators of TRPM8 TRPM8, TRPM4, TRPM6 XDH 3959/4885SYNJ2 1504/4885RECQL 3331/4885
US-20190177308-A9 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 TRPM8, TRPM6, TRPM4 XDH 3531/4885SYNJ2 827/4885RECQL 2141/4885
US-20180273517-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 TRPM8, TRPM6, TRPM4 XDH 3531/4885SYNJ2 827/4885RECQL 2141/4885
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME PIGS, TAS2R13, CEL XDH 4695/4885SYNJ2 2149/4885RECQL 4690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.