Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GPR39 | O43194 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198232 | 0.78 | GLS (0.34) | SMN1; SMN2 | |
| SCHEMBL27196337 | 0.75 | CXCR4 (0.42) | NPC1RAB9AHPGDRECQLDPP4 | |
| SCHEMBL28343228 | 0.75 | CYP2D6 (0.53) | HPGDATMMEN1KMT2A | |
| SCHEMBL15888661 | 0.75 | TRPM8 (0.42) | RAB9AHPGDTRPM8MEN1KMT2A | |
| SCHEMBL19742442 | 0.71 | GBA1 (0.47) | — | |
| SCHEMBL14123884 | 0.71 | GBA1 (0.47) | — | |
| SCHEMBL17592449 | 0.70 | HRH1 (0.42) | HPGDRECQLSMN1; SMN2 | |
| SCHEMBL11022813 | 0.66 | CYP2D6 (0.40) | RAB9AMEN1KMT2A | |
| SCHEMBL9209503 | 0.64 | ALDH1A1 (0.41) | SMN1; SMN2TRPM8 | |
| Trifluoroacetic Acid SCHEMBL27196373 | 0.64 | TACR1 (0.44) | TRPM8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294716-A1 | LACTAM INHIBITORS OF FACTOR XA AND METHOD | Bristol-Myers Squibb Company (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001096331-A1 | LACTAM INHIBITORS OF FACTOR XA AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |