Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987962 | 0.78 | NPC1 (0.35) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10809482 | 0.67 | KDM1A (0.46) | — | |
| SCHEMBL9209503 | 0.62 | ALDH1A1 (0.41) | HTR1AKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL17592449 | 0.62 | HRH1 (0.42) | GLSKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL2465174 | 0.62 | HTR1A (0.35) | HTR1AADRA2AADRA2BADRA2CKDM4E | |
| SCHEMBL1507145 | 0.61 | KDM4E (0.42) | HTR1AADRA2AADRA2BADRA2CKDM4E | |
| SCHEMBL21591752 | 0.60 | KDM1A (0.44) | HTR1AADRA2AADRA2BADRA2CKDM4E | |
| SCHEMBL1240091 | 0.60 | ADRA2A (0.50) | HTR1AADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL29898842 | 0.60 | KDM4E (0.41) | HTR1AADRA2AADRA2BADRA2CKDM4E | |
| SCHEMBL6378734 | 0.59 | HRH1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687249-A1 | BALANOIDS | ELI LILLY AND COMPANY (US) | 1995-12-20 | — | — | EP | disclosed |