Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988714 | 0.88 | SIRT2 (0.43) | ALDH1A1ABL1BCRSRCTBXA2R | |
| SCHEMBL6987131 | 0.88 | GRM5 (0.44) | ALDH1A1TBXA2RTBXAS1MEN1KMT2A | |
| SCHEMBL6986333 | 0.88 | MEN1 (0.48) | ALDH1A1TBXA2RTBXAS1RAB9AMEN1 | |
| SCHEMBL6989487 | 0.86 | ALDH1A1 (0.49) | ALDH1A1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL6988688 | 0.84 | ABCC9 (0.41) | TBXA2RTBXAS1RAB9ALMNATSHR | |
| SCHEMBL6990458 | 0.84 | CSF1R (0.44) | ALDH1A1TBXA2RTBXAS1RAB9AMEN1 | |
| SCHEMBL6988180 | 0.84 | NAMPT (0.51) | ALDH1A1RAB9AKMT2ALMNAMAPT | |
| SCHEMBL6981925 | 0.83 | NAMPT (0.50) | RAB9AMEN1KMT2ALMNAKDM4E | |
| SCHEMBL6988046 | 0.79 | CYP1A2 (0.45) | ALPLALDH1A1ABL1BCRSRC | |
| SCHEMBL4367794 | 0.78 | GRM5 (0.45) | RAB9AMEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358160-A1 | AMINAL DIONES AS POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002062761-A1 | AMINAL DIONES AS POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2002-08-15 | — | — | WO | disclosed |