Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2268660 | 0.78 | KCNN4 (0.38) | TSHRSIGMAR1ALDH1A1MAPTGAA | |
| SCHEMBL10628251 | 0.75 | SIGMAR1 (0.53) | HTTTSHRSIGMAR1ALDH1A1KDM4E | |
| SCHEMBL2100789 | 0.71 | GAA (0.34) | HTTSIGMAR1MAPTGAAKDM4E | |
| SCHEMBL7408511 | 0.71 | HTT (0.37) | HTTTSHRSIGMAR1BCHEACHE | |
| SCHEMBL2100765 | 0.69 | KCNH2 (0.37) | SIGMAR1ALDH1A1MAPTNPSR1KDM4E | |
| SCHEMBL2268688 | 0.68 | SIGMAR1 (0.34) | HTTTSHRSIGMAR1ALDH1A1MAPT | |
| SCHEMBL114779 | 0.67 | LTA4H (0.38) | TSHRSIGMAR1 | |
| SCHEMBL417994 | 0.67 | LTA4H (0.38) | TSHRSIGMAR1NPSR1 | |
| SCHEMBL49577 | 0.67 | ALDH1A1 (0.73) | HTTBCHEALDH1A1MAPTNPSR1 | |
| Biphenyl SCHEMBL7742046 | 0.67 | SIGMAR1 (0.59) | TSHRSIGMAR1ALDH1A1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6765089-B1 | FOR USE IN THE SYNTHESIS OF PEPTIDES, OLIGOSACCHARIDES, GLYCOPEPTIDES AND GLYCOLIPIDS | ALCHEMIA PTY LTD (AU) | 2004-07-20 | — | — | US | disclosed |
| EP-1017683-A4 | PROTECTING AND LINKING GROUPS FOR ORGANIC SYNTHESIS | ALCHEMIA PTY LTD (AU) | 2002-03-06 | — | — | EP | disclosed |
| EP-1017683-A1 | PROTECTING AND LINKING GROUPS FOR ORGANIC SYNTHESIS | Alchemia Pty. Ltd. (AU) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015510-A1 | PROTECTING AND LINKING GROUPS FOR ORGANIC SYNTHESIS | ALCHEMIA PTY. LTD. (AU) | 1999-04-01 | — | — | WO | disclosed |