SCHEMBL2268688

SCHEMBL2268688

CCCC[SiH](NCC)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.34
CA12 O43570 2/20 0.34
CA9 Q16790 2/20 0.34
NPSR1 Q6W5P4 2/20 0.33
HTT P42858 2/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
ALOX12 P18054 1/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
PCSK9 Q8NBP7 1/20 0.32
LTA4H P09960 1/20 0.32
ALDH1A1 P00352 3/20 0.32
TSHR P16473 2/20 0.32
NAAA Q02083 1/20 0.32
PTGS2 P35354 1/20 0.32
KCNN4 O15554 1/20 0.31
HPGD P15428 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CES2 O00748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2267110 0.88 KCNN4 (0.33) SIGMAR1GAAALDH1A1KCNN4HPGD
SCHEMBL2101841 0.86 SIGMAR1 (0.34) SIGMAR1CA12CA9
SCHEMBL2268690 0.82 SIGMAR1 (0.35) SIGMAR1CA12CA9NPSR1HTT
SCHEMBL2101844 0.81 CACNA2D1 (0.37) SIGMAR1
SCHEMBL2269967 0.79 KCNN4 (0.35) SIGMAR1KCNN4
SCHEMBL2103965 0.78 TAAR1 (0.38) SIGMAR1HTTMAPTLTA4HALDH1A1
SCHEMBL2102165 0.74 GAA (0.31) HTTGAA
SCHEMBL2270813 0.73 ALDH1A1 (0.34) ALDH1A1TSHRKCNN4
SCHEMBL114779 0.73 LTA4H (0.38) SIGMAR1PCSK9LTA4HTSHRPTGS2
SCHEMBL417994 0.73 LTA4H (0.38) SIGMAR1NPSR1PCSK9LTA4HTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed