Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9052695 | 0.77 | NPC1 (0.54) | NPC1RAB9AMETAP2KDM4EALDH1A1 | |
| SCHEMBL3464853 | 0.72 | PDPK1 (0.58) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL19676856 | 0.71 | PDPK1 (0.40) | GAAMEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL15375205 | 0.71 | CA2 (0.33) | CA2 | |
| SCHEMBL14624000 | 0.71 | RAB9A (0.55) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL863740 | 0.69 | NOTUM (0.36) | RAB9AKDM4EHSD17B10MEN1ALOX15 | |
| SCHEMBL5020207 | 0.69 | NPC1 (0.59) | NPC1RAB9AMETAP2KDM4EALDH1A1 | |
| SCHEMBL30036439 | 0.69 | MAOB (0.63) | NPC1RAB9AMETAP2KDM4EALDH1A1 | |
| SCHEMBL103158 | 0.69 | MAOB (0.63) | NPC1RAB9AMETAP2KDM4EALDH1A1 | |
| SCHEMBL15360250 | 0.68 | PDPK1 (0.43) | ALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312622-A1 | Process for the preparation of linear or branched 1,4-cis polybutadiene | ENI S.p.A. (IT) | 2003-05-21 | — | — | EP | disclosed |