Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 7/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC1A5 | Q15758 | 4/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989551 | 0.94 | KDM4C (0.43) | HRH1FFAR1LPAR1LPAR5PHF8 | |
| SCHEMBL6232235 | 0.80 | KDM4A (0.43) | MAPTKDM4CTSHRRAF1MAP2K1 | |
| SCHEMBL6989792 | 0.79 | MEN1 (0.45) | LPAR1LPAR5LMNAMAPTKDM4C | |
| SCHEMBL5212416 | 0.77 | KMT2A (0.52) | MAPT | |
| SCHEMBL6232231 | 0.75 | KDM4A (0.52) | MAPTKDM4CTSHR | |
| SCHEMBL6985002 | 0.74 | KDM4E (0.42) | LPAR1LPAR5MAPTKDM4C | |
| SCHEMBL6988723 | 0.74 | SMN1; SMN2 (0.47) | MAPTKDM4CTSHRRAF1MAP2K1 | |
| SCHEMBL6986949 | 0.74 | SLC2A1 (0.48) | LPAR1LPAR5 | |
| SCHEMBL6989317 | 0.73 | SMN1; SMN2 (0.47) | LMNAMAPT | |
| SCHEMBL6988726 | 0.72 | PTGDR2 (0.47) | HRH1LMNAMAPTSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |