Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 5/20 | 0.48 |
| ▸ | SLC2A4 | P14672 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.47 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.45 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986947 | 0.93 | LPAR1 (0.51) | SLC2A1SLC2A4POLBHPGDRECQL | |
| SCHEMBL6989317 | 0.90 | SMN1; SMN2 (0.47) | SLC2A1SLC2A4POLBPTGDR2CHRM2 | |
| SCHEMBL6990355 | 0.88 | SLC2A1 (0.61) | SLC2A1SLC2A4POLBHPGDRECQL | |
| SCHEMBL6990114 | 0.87 | LPAR1 (0.49) | SLC2A1SLC2A4HPGDNR3C2LPAR1 | |
| SCHEMBL6989313 | 0.83 | SMN1; SMN2 (0.47) | POLBLPAR1LPAR5PTGDR2 | |
| SCHEMBL6989792 | 0.82 | MEN1 (0.45) | LPAR1LPAR5 | |
| SCHEMBL6993032 | 0.82 | KMT2A (0.49) | AOC3 | |
| SCHEMBL6990109 | 0.80 | LPAR1 (0.53) | SLC2A1POLBNR3C2LPAR1LPAR5 | |
| SCHEMBL6239726 | 0.78 | ALDH1A1 (0.46) | — | |
| SCHEMBL6985934 | 0.78 | MAPT (0.43) | SLC2A1POLBHPGDNR3C2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |