SCHEMBL698985

SCHEMBL698985

O=C(c1ccc(F)cc1)c1ccc(Cl)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.64
SRD5A2 P31213 1/20 0.64
LTA4H P09960 1/20 0.59
VNN1 O95497 1/20 0.57
HPGD P15428 2/20 0.55
ALDH1A1 P00352 3/20 0.55
HTT P42858 1/20 0.55
CES2 O00748 2/20 0.54
CES1 P23141 2/20 0.54
TSHR P16473 2/20 0.52
ALOX15 P16050 1/20 0.52
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
TP53 P04637 2/20 0.50
LMNA P02545 1/20 0.50
ALPG P10696 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HSP90AA1 P07900 1/20 0.50
KDM4E B2RXH2 1/20 0.50
NPC1 O15118 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9421734 1.00 MAPK1 (0.64) MAPK1SRD5A2LTA4HVNN1HPGD
SCHEMBL9777083 0.88 HPGD (0.59) MAPK1SRD5A2LTA4HVNN1HPGD
SCHEMBL51827 0.87 SRD5A2 (0.80) MAPK1SRD5A2HPGDALDH1A1HTT
SCHEMBL9065412 0.87 SRD5A2 (0.80) MAPK1SRD5A2HPGDALDH1A1HTT
SCHEMBL10697158 0.87 SRD5A2 (0.80) MAPK1SRD5A2HPGDALDH1A1HTT
SCHEMBL1681512 0.87 SRD5A2 (0.80) MAPK1SRD5A2HPGDALDH1A1HTT
SCHEMBL1736339 0.87 LTA4H (0.73) MAPK1SRD5A2LTA4HHPGDALDH1A1
SCHEMBL8572071 0.87 LTA4H (0.73) MAPK1SRD5A2LTA4HHPGDALDH1A1
SCHEMBL238259 0.87 LTA4H (0.73) MAPK1SRD5A2LTA4HHPGDALDH1A1
SCHEMBL10426597 0.87 ALDH1A1 (0.57) MAPK1SRD5A2LTA4HVNN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 517 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037164-A Polyaryletherketone sequence copolymer, preparation method thereof and application thereof in 3D printing 吉林大学 2026-05-15 CN claimed
US-20250215152-A1 POLYARYLETHERKETONE WITH WIDE MOLECULAR WEIGHT DISTRIBUTION AND PREPARATION METHOD THEREFOR JILIN JOINATURE POLYMER CO., LTD. (CN) 2025-07-03 US claimed
CN-120157870-A Polyether-ether-ketone resin with adjustable molecular weight distribution, and synthetic method and application thereof 吉林省中研高分子材料股份有限公司 2025-06-17 CN claimed
EP-4495166-A1 POLYARYLETHERKETONE WITH WIDE MOLECULAR WEIGHT DISTRIBUTION AND PREPARATION METHOD THEREFOR Jilin Joinature Polymer Co., Ltd. (CN) 2025-01-22 EP claimed
CN-113651954-B Composition for synthesizing polyether-ether-ketone, synthetic method of polyether-ether-ketone and polyether-ether-ketone 吉林省中研高分子材料股份有限公司 2024-07-19 CN claimed
CN-113563578-B Method for preparing poly (aryl ether ketone) and poly (aryl ether ketone) 吉林省中研高分子材料股份有限公司 2023-12-26 CN claimed
WO-2023202616-A1 POLYARYLETHERKETONE WITH WIDE MOLECULAR WEIGHT DISTRIBUTION AND PREPARATION METHOD THEREFOR 吉林省中研高分子材料股份有限公司 2023-10-26 WO claimed
CN-115636933-B Polyaryletherketone with wide molecular weight distribution and preparation method thereof 吉林省中研高分子材料股份有限公司 2023-08-04 CN claimed
CN-115636933-A9 Polyaryletherketone with wide molecular weight distribution and preparation method thereof 吉林省中研高分子材料股份有限公司 2023-04-25 CN claimed
CN-113527661-B Preparation method of poly (aryl ether ketone) and poly (aryl ether ketone) 吉林省中研高分子材料股份有限公司 2022-07-15 CN claimed
US-20210292264-A1 Process for Manufacture of Fluorinated Benzenes and Fluorinated Benzophenones, and Derivatives Thereof FUJIAN YONGJING TECHNOLOGY CO., LTD (CN) 2021-09-23 US claimed
US-20200262776-A1 New Process for the Manufacture of Fluorinated Benzenes and Fluorinated Benzophenones, and Derivatives Thereof FUJIAN YONGJING TECHNOLOGY CO., LTD (CN) 2020-08-20 US claimed
US-20170022322-A1 New polymeric materials SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-01-26 US claimed
EP-3097136-A1 NEW POLYMERIC MATERIALS Solvay Specialty Polymers USA, L.L.C. (US) 2016-11-30 EP claimed
WO-2015110477-A1 NEW POLYMERIC MATERIALS SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2015-07-30 WO claimed
EP-0185317-B1 Crystalline aromatic polyketone and process for producing the same ASAHI CHEMICAL IND (JP) 1994-03-16 EP claimed
EP-0184458-B1 THERMOPLASTIC AROMATIC POLYETHERKETONES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-10-18 EP claimed
US-4772679-A CONTAINING SULFIDE LINKAGE, HEAT RESISTANCE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-09-20 US claimed
EP-0185317-A2 Crystalline aromatic polyketone and process for producing the same Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-06-25 EP claimed
EP-0184458-A2 Thermoplastic aromatic polyetherketones IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-06-11 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200262776-A1 New Process for the Manufacture of Fluorinated Benzenes and Fluorinated Benzophenones, and Derivatives Thereof PFAS, PFKFB4, PFKFB1 MAPK1 1831/4885SRD5A2 2602/4885LTA4H 1550/4885
US-20210292264-A1 Process for Manufacture of Fluorinated Benzenes and Fluorinated Benzophenones, and Derivatives Thereof PFAS, PFKFB4, PFKFB2 MAPK1 1943/4885SRD5A2 2658/4885LTA4H 1536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.