Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.34 |
| ▸ | SALL4 | Q9UJQ4 | 1/20 | 0.32 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6314632 | 0.82 | KMT2A (0.38) | MEN1KMT2AMAPTNSD2OPRM1 | |
| SCHEMBL6985038 | 0.80 | HTR2B (0.36) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL6987657 | 0.78 | HTR2B (0.42) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6988447 | 0.77 | ALOX5 (0.33) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL6981245 | 0.76 | KDM4E (0.38) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL6986273 | 0.73 | HTR2B (0.34) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4952161 | 0.72 | TYR (0.35) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL6985040 | 0.68 | KDM4E (0.40) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| Acetic Acid SCHEMBL28608130 | 0.67 | MAPT (0.56) | MEN1KMT2AMAPTNSD2OPRM1 | |
| SCHEMBL10963143 | 0.66 | KDM4E (0.35) | MEN1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1302467-A2 | Process for the preparation of substituted thiazoline derivatives and their intermediate | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2003-04-16 | — | — | EP | disclosed |