Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986273 | 0.90 | HTR2B (0.34) | HTR2BALDH1A1HPGDKDM4ECYP2D6 | |
| SCHEMBL6985038 | 0.86 | HTR2B (0.36) | HTR2BALDH1A1HPGDKDM4ECYP2D6 | |
| SCHEMBL4952161 | 0.85 | TYR (0.35) | ALDH1A1HPGDKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL6985974 | 0.83 | KDM4E (0.37) | ALDH1A1HPGDKDM4EMAPTTHRB | |
| SCHEMBL6988447 | 0.83 | ALOX5 (0.33) | ALDH1A1HPGDKDM4ESMN1; SMN2MAPT | |
| SCHEMBL6982545 | 0.83 | ALOX5 (0.33) | ALDH1A1HPGDKDM4ESMN1; SMN2MAPT | |
| SCHEMBL6985040 | 0.81 | KDM4E (0.40) | ALDH1A1HPGDKDM4ERAB9ANPC1 | |
| SCHEMBL1534233 | 0.79 | HTR2B (0.44) | HTR2BALDH1A1HPGDKDM4ECYP2D6 | |
| SCHEMBL6989995 | 0.78 | MEN1 (0.39) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL6981245 | 0.77 | KDM4E (0.38) | ALDH1A1HPGDKDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1302467-A2 | Process for the preparation of substituted thiazoline derivatives and their intermediate | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2003-04-16 | — | — | EP | disclosed |