Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982545 | 1.00 | ALOX5 (0.33) | ALOX5SCN1ASCN2ASCN3AALDH1A1 | |
| SCHEMBL6987657 | 0.83 | HTR2B (0.42) | ALDH1A1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL6985038 | 0.80 | HTR2B (0.36) | ALDH1A1MEN1KMT2AGAATDP1 | |
| SCHEMBL6986273 | 0.78 | HTR2B (0.34) | ALDH1A1TDP1KDM4EMAPTHPGD | |
| SCHEMBL6989995 | 0.77 | MEN1 (0.39) | ALDH1A1MEN1KMT2AGAAKDM4E | |
| SCHEMBL5914861 | 0.76 | THRB (0.34) | ALOX5ALDH1A1TDP1MAPTNTRK1 | |
| SCHEMBL3958398 | 0.76 | THRB (0.34) | ALOX5ALDH1A1TDP1MAPTNTRK1 | |
| SCHEMBL6315318 | 0.76 | THRB (0.34) | ALOX5ALDH1A1TDP1MAPTNTRK1 | |
| SCHEMBL4952161 | 0.76 | TYR (0.35) | ALOX5ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL6981245 | 0.76 | KDM4E (0.38) | ALDH1A1MEN1KMT2AGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1302467-A2 | Process for the preparation of substituted thiazoline derivatives and their intermediate | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2003-04-16 | — | — | EP | disclosed |