Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 2/20 | 0.31 |
| ▸ | ACP1 | P24666 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6990034 | 0.94 | P2RY1 (0.34) | P2RY1SLC6A4SLC6A3SLC6A2NR1I2 | |
| SCHEMBL29756206 | 0.81 | MEN1 (0.32) | — | |
| SCHEMBL5545747 | 0.81 | MEN1 (0.32) | — | |
| SCHEMBL6992908 | 0.79 | TLR4 (0.32) | L3MBTL1 | |
| SCHEMBL6995620 | 0.79 | GPR84 (0.38) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL10102260 | 0.78 | GPR84 (0.34) | GPR84 | |
| SCHEMBL7528619 | 0.76 | GPR84 (0.48) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL17929234 | 0.75 | ACP1 (0.34) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL7782083 | 0.74 | KDM4E (0.44) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL7529928 | 0.73 | GPR84 (0.46) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0926146-B1 | CHROMENE COMPOUNDS | TOKUYAMA CORP (JP) | 2003-02-12 | — | — | EP | claimed |
| EP-0926146-B1 | CHROMENE COMPOUNDS | TOKUYAMA CORP (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-6197225-B1 | PHOTOCHROMIC LENS MADE OF A POLYMER OF A PHOTOCHROMIC POLYMERIZABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-0926146-A1 | CHROMENE COMPOUNDS | TOKUYAMA CORPORATION (JP) | 1999-06-30 | — | — | EP | disclosed |