Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978583 | 0.87 | NPC1 (0.35) | GPR84MAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7528619 | 0.85 | GPR84 (0.48) | GPR84KDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7529928 | 0.84 | GPR84 (0.46) | GPR84KDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7782083 | 0.83 | KDM4E (0.44) | GPR84KDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1845200 | 0.82 | MEN1 (0.35) | GPR84KDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1844408 | 0.82 | NFKB1 (0.37) | GPR84KDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL17929234 | 0.81 | ACP1 (0.34) | GPR84KDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7528995 | 0.80 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL12659492 | 0.80 | MAPT (0.35) | KDM4EMAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL12205494 | 0.79 | ACHE (0.38) | KDM4EMAPTSMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0926146-B1 | CHROMENE COMPOUNDS | TOKUYAMA CORP (JP) | 2003-02-12 | — | — | EP | claimed |