Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.32 |
| ▸ | CASR | P41180 | 2/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6990194 | 0.94 | KDM4E (0.33) | P2RY1ACP1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL29756206 | 0.87 | MEN1 (0.32) | — | |
| SCHEMBL5545747 | 0.87 | MEN1 (0.32) | — | |
| SCHEMBL10102260 | 0.84 | GPR84 (0.34) | — | |
| SCHEMBL8038479 | 0.77 | AHR (0.38) | KIF11 | |
| SCHEMBL6992908 | 0.76 | TLR4 (0.32) | — | |
| SCHEMBL7562196 | 0.74 | AHR (0.36) | — | |
| SCHEMBL5543986 | 0.73 | GPR84 (0.33) | — | |
| SCHEMBL8978583 | 0.72 | NPC1 (0.35) | — | |
| SCHEMBL13880285 | 0.72 | PGR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0926146-B1 | CHROMENE COMPOUNDS | TOKUYAMA CORP (JP) | 2003-02-12 | — | — | EP | claimed |
| EP-0926146-B1 | CHROMENE COMPOUNDS | TOKUYAMA CORP (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-6197225-B1 | PHOTOCHROMIC LENS MADE OF A POLYMER OF A PHOTOCHROMIC POLYMERIZABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-0926146-A1 | CHROMENE COMPOUNDS | TOKUYAMA CORPORATION (JP) | 1999-06-30 | — | — | EP | disclosed |