Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.30 |
| ▸ | KRAS | P01116 | 1/20 | 0.30 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5545747 | 0.81 | MEN1 (0.32) | — | |
| SCHEMBL29756206 | 0.81 | MEN1 (0.32) | — | |
| SCHEMBL6990194 | 0.79 | KDM4E (0.33) | L3MBTL1 | |
| SCHEMBL10102260 | 0.78 | GPR84 (0.34) | — | |
| SCHEMBL6990034 | 0.76 | P2RY1 (0.34) | — | |
| SCHEMBL7562196 | 0.73 | AHR (0.36) | L3MBTL1 | |
| SCHEMBL8038479 | 0.71 | AHR (0.38) | L3MBTL1 | |
| SCHEMBL13880285 | 0.71 | PGR (0.38) | — | |
| SCHEMBL7128153 | 0.70 | PDE4D (0.40) | L3MBTL1NQO1KRASSOS1PTGES | |
| SCHEMBL6995620 | 0.70 | GPR84 (0.38) | L3MBTL1ABCG2ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0926146-B1 | CHROMENE COMPOUNDS | TOKUYAMA CORP (JP) | 2003-02-12 | — | — | EP | claimed |
| EP-0926146-B1 | CHROMENE COMPOUNDS | TOKUYAMA CORP (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-6197225-B1 | PHOTOCHROMIC LENS MADE OF A POLYMER OF A PHOTOCHROMIC POLYMERIZABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-0926146-A1 | CHROMENE COMPOUNDS | TOKUYAMA CORPORATION (JP) | 1999-06-30 | — | — | EP | disclosed |