Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1845591 | 0.90 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL29565491 | 0.89 | SLC16A3 (0.41) | KDM4EALDH1A1HPGDCDC25BHSD17B10 | |
| SCHEMBL23800896 | 0.89 | SLC16A3 (0.41) | KDM4EALDH1A1HPGDCDC25BHSD17B10 | |
| SCHEMBL26290020 | 0.89 | GPR35 (0.40) | KDM4EALDH1A1HPGDCDC25BHSD17B10 | |
| SCHEMBL26289884 | 0.85 | IDO1 (0.38) | KDM4EALDH1A1HPGDCDC25BHSD17B10 | |
| SCHEMBL7941259 | 0.85 | SLC16A3 (0.38) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL26290022 | 0.83 | KDM4E (0.45) | KDM4EALDH1A1HPGDGPR84HSD17B10 | |
| SCHEMBL6995620 | 0.83 | GPR84 (0.38) | KDM4EALDH1A1HPGDCDC25BGPR84 | |
| SCHEMBL7528619 | 0.82 | GPR84 (0.48) | KDM4EALDH1A1HPGDGPR84NPC1 | |
| SCHEMBL7936515 | 0.81 | KEAP1 (0.42) | KDM4EALDH1A1HPGDRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140892-A1 | PHOTOCHROMIC SUBSTIITUTED 2H-NAPHTHO[1,2-B]PYRANS | JAMES ROBINSON LIMITED (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035902-A1 | PHOTOCHROMIC SUBSTITUTED 2H-NAPHTHO[1,2-b]PYRANS | JAMES ROBINSON LIMITED (GB) | 2000-06-22 | — | — | WO | disclosed |