Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6997763 | 1.00 | P2RX7 (0.43) | P2RX7ALDH1A1LMNAKDM4EHSD11B1 | |
| SCHEMBL7186992 | 0.78 | ALDH1A1 (0.53) | ALDH1A1LMNAKDM4EKMT2AHPGD | |
| SCHEMBL15894814 | 0.68 | CYP1A2 (0.43) | ALDH1A1LMNAHSD11B1USP2SMN1; SMN2 | |
| SCHEMBL6056281 | 0.68 | CYP1A2 (0.53) | ALDH1A1LMNAHSD11B1USP2SMN1; SMN2 | |
| SCHEMBL5392232 | 0.68 | CYP1A2 (0.53) | ALDH1A1LMNAHSD11B1USP2SMN1; SMN2 | |
| SCHEMBL5384869 | 0.68 | CYP1A2 (0.53) | ALDH1A1LMNAHSD11B1USP2SMN1; SMN2 | |
| SCHEMBL5529607 | 0.68 | CYP1A2 (0.53) | ALDH1A1LMNAHSD11B1USP2SMN1; SMN2 | |
| SCHEMBL5406229 | 0.68 | CYP1A2 (0.53) | ALDH1A1LMNAHSD11B1USP2SMN1; SMN2 | |
| SCHEMBL6879832 | 0.68 | CYP1A2 (0.53) | ALDH1A1LMNAHSD11B1USP2SMN1; SMN2 | |
| SCHEMBL14559638 | 0.67 | HSD11B1 (0.49) | ALDH1A1HSD11B1KMT2AGRIN2BHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152779-A1 | Bicyclic amino acids as pharmaceutical agents | BRYANS JUSTIN STEPHEN (GB) | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152779-A1 | Bicyclic amino acids as pharmaceutical agents | AADAT, SLC1A2, BCAT1 | P2RX7 438/4885ALDH1A1 1224/4885LMNA 1221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.