Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | IRAK4 | Q9NWZ3 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29500516 | 0.83 | LMNA (0.57) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL18537879 | 0.83 | LMNA (0.57) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL31154057 | 0.81 | MEN1 (0.54) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL19329732 | 0.80 | IRAK4 (0.52) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL19329541 | 0.79 | RIPK1 (0.54) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL5743889 | 0.79 | SMN1; SMN2 (0.74) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL25956596 | 0.78 | IRAK4 (0.83) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL17488032 | 0.77 | RAB9A (0.67) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL4578043 | 0.77 | IRAK4 (0.49) | MEN1KMT2AMAPTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL27631617 | 0.77 | IRAK4 (0.54) | MEN1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150203812-A1 | Inhibitors of Voltage Gated Ion Channels | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-07-23 | — | — | US | disclosed |
| EP-0920314-B1 | NON-PEPTIDE G-CSF MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2003-08-27 | — | — | EP | disclosed |
| EP-0920314-A4 | NON-PEPTIDE G-CSF MIMETICS | SMITHKLINE BEECHAM CORP (US) | 2001-08-16 | — | — | EP | disclosed |
| US-5981551-A | GRANULOCYTE COLONY-STIMULATING FACTOR MIMETICS; TREATMENT OF NEUTROPENIA | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0920314-A1 | NON-PEPTIDE G-CSF MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-06-09 | — | — | EP | disclosed |
| WO-1997044033-A1 | NON-PEPTIDE G-CSF MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-11-27 | — | — | WO | disclosed |
| US-5384385-A | Adhesives | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-24 | — | — | US | disclosed |
| EP-0543250-A1 | Reactive masses of two-component polyurethanes | BAYER AG (DE) | 1993-05-26 | — | — | EP | disclosed |
| US-3935314-A | Anti-hypertensive compositions of benzimidazole derivatives | BEECHAM GROUP LIMITED (EN) | 1976-01-27 | — | — | US | disclosed |