Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986415 | 0.74 | RAB9A (0.52) | ALDH1A1KMT2AMEN1POLBALOX15 | |
| SCHEMBL6991349 | 0.72 | SMN1; SMN2 (0.52) | KMT2AMEN1POLBHTTRAB9A | |
| SCHEMBL6988214 | 0.70 | GAK (0.49) | ALDH1A1KMT2AMEN1POLBHTT | |
| SCHEMBL7141571 | 0.70 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1POLBALOX15 | |
| SCHEMBL22983039 | 0.69 | CYP11B1 (0.74) | ALDH1A1KMT2AMEN1POLBRAB9A | |
| SCHEMBL7701971 | 0.68 | MEN1 (0.45) | KMT2AMEN1HTTL3MBTL1RAB9A | |
| SCHEMBL2339343 | 0.67 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1POLBALOX15 | |
| SCHEMBL27754792 | 0.66 | ROCK2 (0.66) | ALDH1A1KMT2AMEN1RAB9AGAA | |
| SCHEMBL1971026 | 0.65 | NAMPT (0.78) | ALDH1A1KMT2AHTTRAB9AGAA | |
| SCHEMBL8252721 | 0.65 | RAB9A (1.00) | ALDH1A1KMT2APOLBRAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303508-A1 | SUBSTITUTED 1-(4-AMINOPHENYL)INDOLES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | Boehringer Ingelheim Pharmaceuticals, Inc. (US) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002006273-A1 | SUBSTITUTED 1-(4-AMINOPHENYL)INDOLES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-01-24 | — | — | WO | disclosed |