Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6991349 | 0.80 | SMN1; SMN2 (0.52) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7701943 | 0.72 | MEN1 (0.45) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6988214 | 0.69 | GAK (0.49) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7167309 | 0.68 | TSHR (0.49) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6985373 | 0.68 | KHK (0.45) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6990762 | 0.68 | ALDH1A1 (0.56) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6885464 | 0.67 | ROCK2 (0.58) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6986415 | 0.67 | RAB9A (0.52) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3178619 | 0.67 | NPC1 (0.72) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7091715 | 0.67 | MEN1 (0.43) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6353007-B1 | ANTIINFLAMMATORY AGENTS AND INHIBITORS OF CELLULAR POLIFERATION | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-03-05 | — | — | US | disclosed |