Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30250427 | 1.00 | BRD4 (0.40) | BRD4OPRM1IDO1TDO2GAA | |
| SCHEMBL31305217 | 0.87 | MAPT (0.35) | IDO1TDO2GAATSHRHSD17B10 | |
| SCHEMBL7562619 | 0.81 | P2RX4 (0.41) | GAATSHRHSD17B10MAPTALDH1A1 | |
| SCHEMBL23629627 | 0.68 | SMN1; SMN2 (0.41) | OPRM1GAATSHRMAPTALDH1A1 | |
| SCHEMBL27957994 | 0.68 | TSHR (0.41) | BRD4OPRM1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL30183273 | 0.67 | TSHR (0.40) | BRD4OPRM1TSHRHSD17B10MAPT | |
| SCHEMBL10980767 | 0.67 | ALDH1A1 (0.38) | BRD4IDO1TDO2GAAHSD17B10 | |
| SCHEMBL6097775 | 0.66 | ALDH1A1 (0.41) | IDO1GAATSHRHSD17B10MAPT | |
| SCHEMBL7159138 | 0.65 | MAPT (0.45) | GAAMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL984966 | 0.64 | MAPT (0.41) | IDO1GAAHSD17B10MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230220036-A1 | IMPROVED PROCESS FOR THE PREPARATION OF SEMAGLUTIDE | NEULAND LABORATORIES LTD (IN) | 2023-07-13 | — | — | US | claimed |
| US-20230220036-A1 | IMPROVED PROCESS FOR THE PREPARATION OF SEMAGLUTIDE | NEULAND LABORATORIES LTD (IN) | 2023-07-13 | — | — | US | disclosed |
| EP-0641343-B1 | 4-MERCAPTOACETYLAMINO-[2] BENZAZEPINONE(3) DERIVATIVES, AND USE AS ENKEPHALINASE INHIBITORS | MERRELL PHARMA INC (US) | 2003-06-25 | — | — | EP | disclosed |
| EP-0751783-B1 | HYPOCHOLESTEROLEMIC, ANTIATHEROSCLEROTIC AND HYPOTRIGLYCERIDEMIC USE OF AMINOACETYLMERCAPTO DERIVATIVES | MERRELL PHARMA INC (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0625987-B1 | AMINOACETYLMERCAPTOACETYLAMIDE DERIVATIVES USEFUL AS INHIBITORS OF ENKEPHALINASE AND ACE | MERRELL PHARMA INC (US) | 1998-04-01 | — | — | EP | disclosed |
| US-5624921-A | Hypotriglyceridemic aminoacetylmercapto derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-04-29 | — | — | US | disclosed |
| US-5602122-A | Method for lowering total serum cholesterol and treating hypercholesterolemia with aminoacetylmercapto derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-02-11 | — | — | US | disclosed |
| EP-0751783-A1 | HYPOCHOLESTEROLEMIC, ANTIATHEROSCLEROTIC AND HYPOTRIGLYCERIDEMIC AMINOACETYLMERCAPTO DERIVATIVES | MERRELL PHARMACEUTICALS INC. (US) | 1997-01-08 | — | — | EP | disclosed |
| US-5529995-A | Aminoacetylmercapto derivatives useful as inhibitors of enkephalinase and ACE | MERRELL DOW PHARMACEUTICALS INC. (US) | 1996-06-25 | — | — | US | disclosed |
| US-5488048-A | Aminoacetylmercapto derivatives useful as inhibitors of enkephalinase and ace | MERRELL DOW PHARMACEUTICALS INC. (US) | 1996-01-30 | — | — | US | disclosed |
| WO-1995025532-A1 | HYPOCHOLESTEROLEMIC, ANTIATHEROSCLEROTIC AND HYPOTRIGLYCERIDEMIC AMINOACETYLMERCAPTO DERIVATIVES | MERRELL PHARMACEUTICALS INC. (US) | 1995-09-28 | — | — | WO | disclosed |
| US-5424425-A | Aminoacetylmercapto derivatives useful as inhibitors of enkephalinase and ace | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-06-13 | — | — | US | disclosed |
| EP-0641343-A1 | 4-MERCAPTOACETYLAMINO- 2] BENZAZEPINONE(3) DERIVATIVES, AND USE AS ENKEPHALINASE INHIBITORS | MERRELL PHARMACEUTICALS INC. (US) | 1995-03-08 | — | — | EP | disclosed |
| EP-0625987-A1 | AMINOACETYLMERCAPTOACETYLAMIDE DERIVATIVES USEFUL AS INHIBITORS OF ENKEPHALINASE AND ACE | MERRELL PHARMACEUTICALS INC. (US) | 1994-11-30 | — | — | EP | disclosed |
| WO-1993023397-A1 | 4-MERCAPTOACETYLAMINO-[2] BENZAZEPINONE(3) DERIVATIVES, AND USE AS ENKEPHALINASE INHIBITORS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-11-25 | — | — | WO | disclosed |
| US-5238932-A | Mercaptoacetylamide tricyclic derivatives useful as inhibitors of enkephalinase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-08-24 | — | — | US | disclosed |
| WO-1993016103-A1 | AMINOACETYLMERCAPTOACETYLAMIDE DERIVATIVES USEFUL AS INHIBITORS OF ENKEPHALINASE AND ACE | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-08-19 | — | — | WO | disclosed |
| US-4642308-A | ANTICONVULSANTS, ANXIOLYTIC AGENTS, ANTIEPILEPTIC AGENTS, HYPNOTICS, MUSCLE RELAXANTS | RHONE-POULENC SANTE (FR) | 1987-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230220036-A1 | IMPROVED PROCESS FOR THE PREPARATION OF SEMAGLUTIDE | GCG, OGDH, ABAT | BRD4 2713/4885OPRM1 1390/4885IDO1 913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.