Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981925 | 0.82 | NAMPT (0.50) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL6990741 | 0.80 | GABRA5 (0.35) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL6989037 | 0.79 | DDR1 (0.43) | MEN1KMT2ANPC1MAPTCYP1A2 | |
| SCHEMBL6989465 | 0.78 | NPC1 (0.41) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL6983908 | 0.77 | ABCC9 (0.44) | MEN1KMT2ANPC1RAB9ASNCA | |
| SCHEMBL6991687 | 0.76 | KMT2A (0.42) | MEN1KMT2ANPC1RAB9ACYP1A2 | |
| SCHEMBL6986333 | 0.76 | MEN1 (0.48) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL4367794 | 0.75 | GRM5 (0.45) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL6990458 | 0.75 | CSF1R (0.44) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL6988688 | 0.75 | ABCC9 (0.41) | NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358160-A1 | AMINAL DIONES AS POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2003-11-05 | — | — | EP | claimed |
| WO-2002062761-A1 | AMINAL DIONES AS POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2002-08-15 | — | — | WO | claimed |