SCHEMBL4174559

SCHEMBL4174559

NCCCCCCN1C(=O)C=CC1=O

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 10/20 0.77
FAAH O00519 5/20 0.77
ALDH1A1 P00352 2/20 0.77
LMNA P02545 2/20 0.77
MAPT P10636 2/20 0.77
NPSR1 Q6W5P4 2/20 0.77
HSP90AA1 P07900 1/20 0.77
TLR9 Q9NR96 1/20 0.77
TP53 P04637 1/20 0.77
PKM P14618 1/20 0.77
HPGD P15428 1/20 0.77
XBP1 P17861 1/20 0.77
MAPK1 P28482 1/20 0.77
HTT P42858 1/20 0.77
RECQL P46063 1/20 0.77
RAB9A P51151 1/20 0.77
SMN1; SMN2 Q16637 1/20 0.77
GPR35 Q9HC97 1/20 0.77
GPR55 Q9Y2T6 1/20 0.77
PTGS1 P23219 7/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9999878 1.00 MGLL (0.77) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL25586313 1.00 MGLL (0.77) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL25586309 1.00 MGLL (0.77) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL25586311 1.00 MGLL (0.77) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL25586310 1.00 MGLL (0.77) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL25586312 1.00 MGLL (0.77) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL338631 1.00 MGLL (0.77) MGLLFAAHALDH1A1LMNAMAPT
Hydrochloric Acid SCHEMBL7515365 0.98 MGLL (0.74) MGLLFAAHALDH1A1LMNAMAPT
Hydrochloric Acid SCHEMBL3402339 0.98 MGLL (0.74) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL2919549 0.98 MGLL (0.76) MGLLFAAHALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0429611-B1 AMINOALKYL MALEIMIDES AND HAPTENE AND ANTIGEN DERIVATIVES THEREOF AND CONJUGATES WITH PEPTIDES OR PROTEINS ROCHE DIAGNOSTICS GMBH (DE) 2001-02-28 EP claimed
EP-0429611-A1 AMINOALKYL MALEIMIDES AND HAPTENE AND ANTIGEN DERIVATIVES THEREOF AND CONJUGATES WITH PEPTIDES OR PROTEINS Roche Diagnostics GmbH (DE) 1991-06-05 EP claimed
WO-1990015798-A1 AMINOALKYL MALEIMIDES AND HAPTENE AND ANTIGEN DERIVATIVES THEREOF AND CONJUGATES WITH PEPTIDES OR PROTEINS BOEHRINGER MANNHEIM GMBH (DE) 1990-12-27 WO claimed
CN-122055379-A Compounds containing one or more diboronate esters and related insulin analogues 普罗托莫科技公司 2026-05-15 CN disclosed
EP-4694932-A2 COMPOUNDS CONTAINING ONE OR MORE DIBORONATES AND RELATED INSULIN ANALOGS Protomer Technologies Inc. (US) 2026-02-18 EP disclosed
WO-2025088200-A2 ACID PHOSPHATASE 3 LIGANDS FOR TARGETED DELIVERY APPLICATIONS PHILOCHEM AG (CH) 2025-05-01 WO disclosed
US-20250099600-A1 Active Metabolites of Kinesin Spindle Protein Inhibitor Conjugates BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2025-03-27 US disclosed
EP-4525919-A1 AROMATIC BORON-CONTAINING COMPOUNDS AND RELATED INSULIN ANALOGS Protomer Technologies Inc. (US) 2025-03-26 EP disclosed
CN-119677541-A Aromatic boron-containing compounds and related insulin analogues 原聚体科技公司 2025-03-21 CN disclosed
US-20240425528-A1 AROMATIC BORON-CONTAINING COMPOUNDS AND RELATED INSULIN ANALOGS PROTOMER TECH INC (US) 2024-12-26 US disclosed
US-20240400637-A1 COMPOUNDS CONTAINING ONE OR MORE DIBORONATES AND RELATED INSULIN ANALOGS PROTOMER TECHNOLOGIES INC. 2024-12-05 US disclosed
EP-1585791-A1 HYDROPHILIC, THIOL-REACTIVE CYANINE DYES AND CONJUGATES THEREOF WITH BIOMOLECULES FOR FLUORESCENCE DIAGNOSIS Schering AG (DE) 2005-10-19 EP disclosed
WO-2004110379-A2 A1 ADENOSINE RECEPTOR ANTAGONISTS ENDACEA, INC. (US) 2004-12-23 WO disclosed
WO-2004065491-A1 HYDROPHILIC, THIOL-REACTIVE CYANINE DYES AND CONJUGATES THEREOF WITH BIOMOLECULES FOR FLUORESCENCE DIAGNOSIS SCHERING AG (DE) 2004-08-05 WO disclosed
EP-0429611-B1 AMINOALKYL MALEIMIDES AND HAPTENE AND ANTIGEN DERIVATIVES THEREOF AND CONJUGATES WITH PEPTIDES OR PROTEINS ROCHE DIAGNOSTICS GMBH (DE) 2001-02-28 EP disclosed
US-5595741-A Aminoalkylmaleimides and hapten and antigen derivatives derived therefrom as well as conjugates with peptides or proteins BOEHRINGER MANNHEIM GMBH (DE) 1997-01-21 US disclosed
EP-0429611-A1 AMINOALKYL MALEIMIDES AND HAPTENE AND ANTIGEN DERIVATIVES THEREOF AND CONJUGATES WITH PEPTIDES OR PROTEINS Roche Diagnostics GmbH (DE) 1991-06-05 EP disclosed
WO-1990015798-A1 AMINOALKYL MALEIMIDES AND HAPTENE AND ANTIGEN DERIVATIVES THEREOF AND CONJUGATES WITH PEPTIDES OR PROTEINS BOEHRINGER MANNHEIM GMBH (DE) 1990-12-27 WO disclosed
EP-0314042-A2 Novel copolymers and superoxide dismutase modified with said copolymers KURARAY CO., LTD. (JP) 1989-05-03 EP disclosed
EP-0306168-A1 Preparation of radiolabeled conjugates IMMUNOMEDICS, INC. (US) 1989-03-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425528-A1 AROMATIC BORON-CONTAINING COMPOUNDS AND RELATED INSULIN ANALOGS IAPP, GPR119, INSR MGLL 3112/4885FAAH 4658/4885ALDH1A1 4080/4885
US-20250099600-A1 Active Metabolites of Kinesin Spindle Protein Inhibitor Conjugates KIF18B, KIF18A, KIF5B MGLL 4551/4885FAAH 4536/4885ALDH1A1 2674/4885
US-20240400637-A1 COMPOUNDS CONTAINING ONE OR MORE DIBORONATES AND RELATED INSULIN ANALOGS GPR119, INSR, IAPP MGLL 937/4885FAAH 4284/4885ALDH1A1 2131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.