Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994495 | 0.86 | KMT2A (0.44) | NR4A2SMN1; SMN2MEN1CYP3A4HPGD | |
| SCHEMBL6991984 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1CYP3A4HPGDKMT2A | |
| SCHEMBL8596365 | 0.76 | MEN1 (0.57) | NR4A2SMN1; SMN2MEN1CYP3A4HPGD | |
| SCHEMBL27659373 | 0.75 | TDP1 (0.41) | NR4A2SMN1; SMN2MEN1CYP3A4HPGD | |
| SCHEMBL9352755 | 0.72 | KMT2A (0.44) | SMN1; SMN2MEN1CYP3A4HPGDKMT2A | |
| SCHEMBL6993582 | 0.71 | KMT2A (0.50) | NR4A2SMN1; SMN2MEN1CYP3A4HPGD | |
| SCHEMBL9398218 | 0.69 | MME (0.38) | NR4A2KMT2ATDP1GAAALDH1A1 | |
| SCHEMBL9398221 | 0.68 | GPR139 (0.53) | NR4A2KMT2ATDP1MAPTGAA | |
| SCHEMBL7716214 | 0.68 | GPR139 (0.53) | NR4A2KMT2ATDP1MAPTGAA | |
| SCHEMBL11276739 | 0.67 | NR4A2 (0.58) | NR4A2SMN1; SMN2MEN1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606683-B1 | Means for diagnosis of angiogenic diseases | DIAGNOSTIKFORSCHUNG INST (DE) | 2003-01-02 | — | — | EP | claimed |
| EP-0606683-B1 | Means for diagnosis of angiogenic diseases | DIAGNOSTIKFORSCHUNG INST (DE) | 2003-01-02 | — | — | EP | disclosed |
| US-6379650-B1 | FOR ENHANCING RADIOIMAGING OF AMYLOID DEPOSITS BY STANDARD NUCLEAR MEDICINE TECHNIQUES | ASHTON WESLEY SCOTT (US) | 2002-04-30 | — | — | US | disclosed |
| EP-0606683-A2 | Means for diagnosis of angiogenic diseases | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) | 1994-07-20 | — | — | EP | disclosed |