Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.56 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2089082 | 0.80 | DYRK1A (0.77) | ALDH1A1KMT2ASMN1; SMN2MKNK1MKNK2 | |
| SCHEMBL6956022 | 0.79 | ALDH1A1 (0.67) | ALDH1A1KMT2ASMN1; SMN2MKNK1MKNK2 | |
| SCHEMBL330565 | 0.79 | ALDH1A1 (0.66) | ALDH1A1KMT2ASMN1; SMN2MKNK1MKNK2 | |
| SCHEMBL4895088 | 0.79 | IKBKB (0.51) | ALDH1A1SMN1; SMN2CYP11B1CYP11B2IKBKB | |
| SCHEMBL2662870 | 0.77 | RAB9A (0.70) | KMT2ASMN1; SMN2MEN1TP53LMNA | |
| SCHEMBL14190747 | 0.76 | LTA4H (0.74) | ALDH1A1KMT2ASMN1; SMN2MKNK1MKNK2 | |
| SCHEMBL17279987 | 0.76 | RAB9A (0.58) | KMT2ASMN1; SMN2CYP11B1CYP11B2TP53 | |
| SCHEMBL26108551 | 0.75 | KDM4E (0.65) | ALDH1A1KMT2ASMN1; SMN2MEN1TP53 | |
| SCHEMBL28573902 | 0.75 | ALDH1A1 (0.71) | ALDH1A1KMT2ASMN1; SMN2MKNK1MKNK2 | |
| SCHEMBL3517442 | 0.73 | CA12 (0.56) | KMT2AMEN1CYP11B1CYP11B2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945438-B1 | PYRAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-6057335-A | Pyrazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0945438-A1 | PYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |